Rated 4.7 (2,091)
4-in-1 NAD+ Longevity & Mobility Complex
A 4-in-1 NAD+ longevity complex designed to support your senior dog's natural cellular energy production, help maintain muscle strength and hind-leg mobility, and support everyday comfort, vitality, and playfulness.†
Energy – Supports cellular energy production as dogs age†
Strength – Helps maintain muscle function and hind-leg power†
Getting Up – Supports the push-off to rise, climb, and jump†
Mobility – Supports comfortable, confident movement all day†
90-Day Money Back Guarantee
See the difference in your dog within 90 days — or get 100% of your money back. No return shipping, no hoops.
Description
It's Always the Back Legs. That's Not a Coincidence.
Every part of your dog's body runs on the same cellular fuel — and when that fuel runs low with age, his body doesn't fail everywhere at once. It triages. The heart, brain, and lungs get first claim, because they keep him alive. The big hind-leg muscles are the body's largest, hungriest "optional" expense — so they're the first thing his body quietly powers down. He isn't giving up. His body is protecting him.
Old Friend Labs delivers four research-backed ingredients per serving to help end the shortage that forces the rationing — supporting your senior dog's natural cellular energy production, muscle function, and everyday mobility.†
NAD+ & NMN, The Supply Pair: NAD+ helps refill the body's energy grid directly; NMN supports the cell's own generators so supply stays up around the clock†
CoQ10, The Converter: Works inside the hind-leg muscle to help turn restored supply into usable power†
Resveratrol, The Delivery Lines: Supports healthy blood-vessel function that carries fuel and oxygen all the way to the back legs — last stop on the route†
Nothing Hidden: Every ingredient and dose fully disclosed on the label — no proprietary blends
The Results
This works with your dog's own cellular rhythms. It's a gradual rebuild, not a painkiller — give it the full cycle rather than judging it in a week.†
Weeks 1 to 3
Energy comes back first — longer walks, more interest in play, less sleeping through the day†
Weeks 4 to 8
Movement gets steadier — rising from the floor, stairs, and slick floors take less effort†
Weeks 8 and beyond
Strength and mobility that hold day to day — so you spend less time helping him up and more time keeping up with him†
90 Day Guarantee
The Empty Bottle Promise.
You've already spent money on chews and bottles that did nothing. We're not asking you to do that again on faith. You have three full months to try it. Use the entire supply.
If you don't see a difference in how he gets up, moves, and plays, contact us for a full refund. You don't even need to send the empty bottles back.
Shipping & Returns
Fast, Free, & Easy.
Fast Shipping
Free US Shipping
Included on all multi-bottle bundles.
Easy Returns
If you aren't happy, our US-based support team processes refunds promptly. No hoops, no cancellation maze.
Frequently Asked Questions
Everything You Want to Know Before You Order
Can I give this alongside his medication?
This is the first question almost everyone asks, and it deserves a straight answer. This formula contains four ingredients your dog's body already knows — NAD+, NMN, CoQ10, and resveratrol — and nothing pharmaceutical. No NSAIDs, no monoclonal antibodies, no sedatives.
That said, we are not your vet and we won't pretend to be. Every ingredient and every dose is printed on the label specifically so you can show it at your next appointment and get an answer for your dog's exact situation — especially if he's on carprofen, gabapentin, or any prescription.
Why not just glucosamine?
Glucosamine and joint chews are built for one thing: cartilage. If your dog's problem were only in his joints, they might be enough.
But if he can still walk fine and struggles to get UP — off the floor, into the car, up the stairs — that's not a cartilage problem. That's an energy problem in the big hind-leg muscles. This formula works on the fuel supply those muscles run on, which is something no cartilage builder was ever designed to touch.†
How do I give it?
One dropper daily, either directly by mouth or mixed into his food — most owners just add it to breakfast. Consistency matters far more than timing.
Each bottle is 60ml, a full 30-day supply for most dogs. Dosing by weight is printed on the label.
I already have a cabinet full of supplements that didn't work. Why is this different?
Because most of what's in that cabinet was built for joints. Cartilage builders feed cartilage. They were never designed for what actually happens as dogs age: cellular fuel runs low, and the body starts rationing — protecting the heart and brain first, and quietly powering down the big hind-leg muscles.
This formula works on the shortage itself, not the joint. That's why it's not competing with what you've tried — it's doing a different job.†
How long until I notice anything?
This is not a painkiller and it will not work like one. Cellular energy support builds gradually, which is why research in this area runs in weeks and months rather than days.
Most owners watch for the small things first: more interest in walks, less sleeping through the day. Give it the full 90 days as part of his daily routine. That is exactly why the guarantee runs that long.
What if it doesn't work for my dog?
You're covered by our 90-Day Empty Bottle Guarantee. Try it for a full 90 days. If you don't see a difference in how he gets up, moves, and plays, contact us within 90 days of your first order for a full refund.
You don't even need to send the bottles back, empty or not.
Real People. Real Results.
I've been giving my 12 year old Lab Casper everything you can think of. Cosequin, Dasuquin, fish oil, you name it. Nothing really moved the needle. About three weeks on Old Friend Labs and my husband said it first: "he's walking different." He's getting up on his own now and following me around the kitchen like he used to.
My Pug Peanut used to just sit and watch the other dogs at the park. Now she's actually joining in. Made me tear up.
My 11 year old Golden Retriever Bella is my baby. Her back legs had gotten so weak she'd slip on the tile and just lay there looking at me. I was scared to try one more thing that didn't work. This one actually did. She's doing the stairs again and jumped onto the couch last night without help.
Tank is my 9 year old Boxer and his energy is back. He brought me his ball this morning for the first time in months.
Honestly I bought this thinking it was another bottle of snake oil. My German Shepherd Rocky is 13 and has bad arthritis in his hind end. After about a month I noticed he wasn't groaning when he stood up anymore. Now he beats me to the door for walks. Night and day difference.
My Bulldog Winston hates taking anything, but he laps this right up out of his food. Moving so much easier now.
Millie is my 14 year old rescue mix and my heart dog. I just wanted to buy her more good time. I honestly wasn't expecting much at her age. Six weeks in and she's got a little bounce back in her walk. She actually chased a squirrel yesterday. First time in over a year. I cried a little.
My little Dachshund Cooper had gotten to where he wouldn't jump off the couch anymore. He'd stand at the edge and cry until I lifted him down. Broke my heart every time. Started this six weeks ago and yesterday he just hopped down like it was nothing. I actually sat there and stared at him.
I'm 71 and my little Yorkie Sadie is 15. My vet basically told me to keep her comfortable and enjoy the time we have left. That was almost a year ago. She's still here, and honestly she's moving better now than she was then. I don't know exactly what's in this stuff but I'm not stopping.
Daisy is 14 and I honestly thought we were near the end. She surprised me. Trotting down the driveway to get the mail with me again.
Otis is only 6 but he's a Mastiff so the wear and tear shows early. This has kept him mobile and playful. Worth every penny.
He Still Walks Fine. So Why Can't He Get Up?
The walks haven't changed. But the floor has become a negotiation — the scramble on the tile, the pause before the stairs, the look he gives you before the car. That isn't him giving up. His body is rationing scarce cellular fuel, protecting his heart and brain first — and quietly powering down the big hind-leg muscles. A simple daily dropper can help.
Four Ingredients, One Shortage
End the rationing at the source
Old Friend Labs delivers NAD+, NMN, CoQ10, and resveratrol in every serving. The first two work on the fuel supply itself — refilling the grid and keeping his own generators running. The third helps convert that supply into power inside the hind-leg muscle. The fourth supports the delivery lines that carry it all the way to the back legs — last stop on the route.†
Supports Daily
Energy
Supports Muscle
Strength
Supports Easier
Rising
Supports All-Day
Mobility
Why NAD+ For Your Dog?
The Ingredient
The Fuel His Cells Run On
NAD+ is the molecule every cell in your dog's body uses to make energy — and levels naturally decline with age. It's the same compound behind the human longevity research, at a dose formulated for dogs.
The Gap
Joint Chews Can't Reach It
Glucosamine feeds cartilage. But cellular fuel isn't in any joint chew, and dogs can't get meaningful amounts from food. That's why the cabinet fills up while the same question stays: why can't he get up?
The Solution
One Dropper, Once Per Day
Old Friend Labs delivers NAD+, NMN, CoQ10, and resveratrol in a fast-absorbing liquid — a meaningful daily dose that goes in his breakfast and takes ten seconds.
NAD+ Declines With Age
Why Daily Support Matters More Over Time
NAD+ plays a key role in how cells produce energy. Research shows the body's natural levels tend to decline significantly with age — in dogs, that decline is well underway by age 7, and earlier in large breeds. That's exactly when the hind legs start losing the fuel they need — and why daily support matters more each year, not less.
We Print Every Dose. Most Brands Don't.
What Old Friend Labs Looks Like Over Time
Week 1-2:
One dropper daily, straight into his breakfast. The goal in the first two weeks is consistency — making it part of the morning routine you already have, so neither of you has to think about it.
Week 3-4:
It works best with steady daily use. Keep the routine going — if it helps, pair the dropper with his breakfast scoop so it never gets skipped, even on busy mornings.
Week 5-8:
By now the dropper should feel automatic. This is when most owners start noticing the moments that matter — and it works best alongside what already helps him: gentle walks, a good bed, traction on slick floors.
Week 9-12+:
This is designed for ongoing daily use through his senior years — alongside whatever his vet has him on — not as a short-term fix. Most owners stay on it because it becomes a simple part of both your mornings.
90 Day Money Back Guarantee
Try it for a full 90 days. If you don't see a difference in how he gets up, moves, and plays, contact us within 90 days of your first order for a full refund. You don't even need to send the bottles back, empty or not.